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Author

Arun Durvasula

2 papers indexed here

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Open access Sep 2026

Accelerated Evolution of Context-Dependent Gene Expression in Primate Immune Cells

Regulatory variation is widely recognized as a driver of evolution within and between species, including in the primate lineage. Evidence for potentially adaptive regulatory evolution in primates comes from both sequence-based tests for selection and cross-species comparisons of gene expression. However, comparative st...

Arun Durvasula, Amy Longtin, Audrey M. Arner et al. · 0 citations
Open access Aug 2026

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection

Causal disease effect sizes of proximal single-nucleotide polymorphisms (SNPs) are widely assumed to be independent but could be correlated. Here we introduce a new method, linkage disequilibrium SNP-pair effect correlation regression (LDSPEC), to estimate the correlation of causal disease effect sizes of derived allel...

M. Zhang, Arun Durvasula, C. Chiang et al. · 0 citations

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