Cell death represents a critical process in the maintenance of cellular homeostasis. Paraptosis, a mechanism of programmed cell death, is distinguished by extensive cytoplasmic vacuolization. We have identified two commercially available compounds, IKK16 and SGI1027, which can induce cytoplasmic vacuolization leading...
Arwa Alsubait, B. Alghanem, H. Ghadbane et al.· Cell Death & Disease· 0 citations
This study identifies a novel regulatory axis involving miR-100, ST6GALNAC4, and TXNDC11 in lung cancer and identifies Vorinostat as a promising candidate for drug repurposing in this context.
B. Alotaibi, Arwa Alsubait· Clinical Cancer Research· 0 citations
This review provides a comprehensive assessment of four major nanoparticle families—polymeric carriers, lipid-based vehicles, inorganic systems, inorganic systems, and hybrid composites—focusing on how their physicochemical properties govern drug encapsulation, release behavior, and tissue compatibility.
Z. Asiri, Abeer Mobarki, Sahar S. Alghamdi et al.· International Journal of Mol...· 0 citations
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