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Author

Asha Thomas

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2 papers indexed here

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Open access Jul 2026

Ebola virus exploits host lncRNA LINC01740 to enhance ATF3 and suppress antiviral immune responses

Ebola virus (EBOV) infection causes severe hemorrhagic fever marked by dysregulated cytokine production, impaired antiviral defenses, and multi-organ failure. Macrophages are primary targets of EBOV, and viral replication profoundly alters macrophage transcriptional programs, driving hyperinflammation. Although long no...

O. Shtanko, Tanuj Gunturu, Anumarla Gopal et al. · 0 citations
Open access Jul 2026

Ebola virus exploits host lncRNA LINC01740 to enhance ATF3 and suppress antiviral immune responses 2259953

A novel LINC01740—ATF3—IFN-I regulatory axis driving immune evasion and viral persistence is shown, highlighting lncRNAs as potential antiviral therapeutic targets and LINC01740 as a novel host lncRNA co-opted by EBOV to enhance ATF3 and suppress antiviral responses.

Narasimha Tanuj Gunturu, Anumarla Gopal, Marija Djurkovic-Lopez et al. · 0 citations

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