Sep 2026
Engineering Poly(ε-caprolactone)-Based Maleimide−Enediyne Micelles for Next-Generation Anticancer Therapies
Inspired by the DNA-cleaving potency of natural enediynes such as calicheamicin, we report the design and synthesis of maleimide−enediyne conjugates integrated into poly(ε-caprolactone) (PCL) as a next-generation platform for anticancer drug delivery. Maleimide-based enediynes typically suffer from poor aqueous solub...
Abhi Bhadran, G. Babanyinah, Himanshu Polara et al.
· Biomacromolecules · 0 citations