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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Asifullah Khan

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Open access Aug 2026

Sequence-Derived Representations versus Pfam-Domain Content for Biosynthetic Gene Cluster Retrieval

Retrieving BGCs related to those of a known producer can be regarded as a representation-learning objective. We hypothesize that ESM-2 sequence-derived representations of BGCs can improve retrieval beyond the Pfam-domain content metric. Our toolkit is the following: group-disjoint train, validation, and test assignment...

Rustambek Urokov, Asifullah Khan, Farhod Eshboyev et al. · 0 citations

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