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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Atanu Sarma

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Open access Jul 2026

Improving the biopharmaceutical performance of azole antifungals: a comparative study of solid dispersion and co-crystallization of ketoconazole and itraconazole

Background: Oral bioavailability of BCS class II azole antifungals, ketoconazole and itraconazole, is hampered by low aqueous solubility. Improving solubility and dissolution is necessary for greater therapeutic efficacy. This research compared two approaches: solid dispersion and pharmaceutical co-crystallization to i...

Payal Dasgupta, Bipul Nath, Apurba Talukdar et al. · 0 citations

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