Author

Athanasios G. Papavassiliou

3 papers indexed here

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Open access Aug 2026

Targeting SUV4–20H2-mediated H4K20 methylation restrains growth and migration in pediatric high-grade astrocytomas

Pediatric astrocytomas are characterized by increased molecular and clinical heterogeneity with epigenetic alterations contributing to aggressiveness and therapy resistance. The repressive histone mark H4K20 trimethylation (H4K20me3) and the methyltransferase SUV4–20H2 (KMT5C) are critical regulators of chromatin integ...

A. Giannopoulou, Elisavet Kosma, Dimitrios S. Kanakoglou et al. · Neurotherapeutics · 0 citations

Open access Sep 2026

Artificial Intelligence as a Catalyst for Novel Therapeutic Opportunities in Precision Oncology

Artificial intelligence (AI) is reshaping molecular oncology by making complex biological data tractable and by extending the reach of precision drug discovery. Its emerging value is particularly evident at the interface of immunoengineering and targeted therapy, where computational models can help prioritize tumor-sel...

K. Papavassiliou, A. Sofianidi, Angeliki Margoni et al. · International Journal of Mol... · 0 citations

Open access Sep 2026

Beyond Sequencing: Integrating MLPA Reveals Hidden Structural PKD2 Variants and Enhances Mutation Detection in a Highly Selected ADPKD Greek Cohort

Background and Objectives: The genetic architecture of late-onset autosomal dominant polycystic kidney disease (ADPKD) remains incompletely defined. Pathogenic mutations in two genes that encode polycystin proteins, PKD1 and PKD2, prevail among these patients. Detection of PKD1 alterations by a sequencing method is cha...

Akrivi Papachristopoulou, Angeliki Margoni, A. Simoudis et al. · Medicina · 0 citations