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Author

Audrianna Kern

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2 papers indexed here

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Oct 2026

B-168 Purified Recombinant Human Albumin Produced in Thermothelomyces heterothallica (C1) Demonstrates Effective Blocking and Comparable Surface Binding to Other Recombinant and Native Albumins

Recombinant and native human serum albumins (rHA and HSA) are widely used as blocking agents to prevent nonspecific binding of enzymes, antibodies, and other biomolecules to surfaces. HSA is primarily used in diagnostic assays to reduce background signals and improve assay sensitivity, though assay performance ca...

Audrianna Kern, A. Okerlund, C. Kunkler et al. · 0 citations
Oct 2026

B-017 A Purified Recombinant Human Albumin Produced in Thermothelomyces heterothallica (C1) Better Mimics Native Human Serum Albumin than Recombinant Albumin from Other Expression Systems

Recombinant human albumin (rHA) is widely used as an alternative to plasma-derived human serum albumin (HSA) in diagnostic and bioanalytical applications. However, rHA produced in different expression systems can exhibit varying post-translational modifications (PTMs), impurity profiles, and free thiol content, w...

Audrianna Kern, Garry Smith, A. Okerlund et al. · 0 citations

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