Exploring the substrate specificity and catalytic mechanism in a PAPS-independent ASST from Salmonella typhimurium
Sulfation plays an important role in many metabolic processes such as substrate detoxification, solubilization or activation. The enzymes responsible for these reactions, sulfotransferases, occur in all domains of life and can be classified in two major, evolutionary independent groups, PAPS-dependent and PAPS independ...