Avani Parikh

Expanding the Antigen Targeting of CAR T Cells via a Universal Bispecific T cell Engager 2259699

Although CAR T cell therapy has shown remarkable clinical effects in the treatment of hematological cancers, the application of CAR T cells to treat solid tumors remains ineffective. Bispecific T cell Engagers (BiTE) are chimeric proteins capable of retargeting T cell receptors (TCR) to specific tumor antigens. C...