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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Axel Guthart

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Open access Aug 2026

Telomerase-Related Gene Expression Networks Predicting Survival in Hepatocellular Carcinoma and Renal Clear Cell Carcinoma

Background: Telomerase is a ribonucleic multimeric reverse transcriptase complex protecting the chromosomal ends from erosion and thereby from cellular senescence. The prognostic value of the components of this complex and their interrelationships with the immune system are not well understood. Objectives: We aimed to...

Axel Guthart, Edna Ooko, Thomas Efferth et al. · 0 citations
Open access Aug 2026

Discovery of the natural product NAT-6-321056 as a novel modulator of VEGFR2 signaling to suppress tumor angiogenesis.

Virtual screening of 39,442 natural products from the ZINC natural product library, coupled with molecular docking and molecular dynamics simulations to evaluate the binding stability of candidate compounds, identified NAT-6-321056 as a highly promising modulator of VEGFR2 signaling and represents a viable candidate fo...

Xiao Lei, W. Gong, Nadine Wiesmann-Imilowski et al. · 0 citations

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