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Aya M. Mustafa

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Open access Sep 2026

Obeticholic acid attenuates complete freund's adjuvant-induced arthritis in rats through FXR-mediated modulation of TGF-β/TAK1/MKK3/p38 MAPK signaling, inflammation, and oxidative stress.

Rheumatoid arthritis is a chronic autoimmune inflammatory disorder characterized by synovial inflammation, oxidative stress, cartilage destruction, and progressive joint damage. Farnesoid X receptor activation has recently emerged as a potential regulator of immune and inflammatory responses. This study investigated th...

Mohamed Magdy Senna, N. A. Shiha, H. Zaki et al. · 0 citations

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