Review
Oct 2026
From CYP450 pharmacogenomics to personalized medicine: clinical evidence, dosing guidelines, and future perspectives.
Interindividual variability in drug response remains a critical challenge in contemporary pharmacotherapy, and cytochrome P450 (CYP450) genetic polymorphisms are a principal determinant of this heterogeneity. The CYP450 superfamily mediates the oxidative biotransformation of 70-80% of clinically prescribed medications....
K. Aldossary, Dalia K. Zaafar, Nada A. Alsaleh et al.
· Pharmacogenomics (London) · 0 citations