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Author

Ayan Dasgupta

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Open access Jul 2026

A versatile strategy for oligonucleotide functionalization via on-support phosphitylation.

Chemically modified nucleic acids such as antisense oligonucleotides, small interfering RNA and CRISPR guide RNA have emerged as transformative modalities in modern medicine, providing new strategies for the treatment of genetic and metabolic disorders, viral infections and cancer. However, their application is limited...

Ayan Dasgupta, S. Golojuch, Li Xiao et al. · 0 citations

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