Early Renal microRNA Signatures of Septic Acute Kidney Injury in Neonatal Pigs.
Acute kidney injury (AKI) is a major complication of neonatal sepsis, yet the early molecular events underlying sepsis-associated AKI (SA-AKI) in the maturing kidney remain poorly defined. MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression that may contribute to the inflammatory, stress, and remo...