Single-cell Transcriptomic Characterization of DPP8 and DPP9 Expression Across Malignant Transcriptional States in Glioblastoma.
Objectives Glioblastoma (GBM) is a grade IV astrocytoma characterized by extensive intratumoral heterogeneity, with malignant cells existing in distinct malignant transcriptional states within the same tumour. DPP8 and DPP9 are intracellular serine proteases implicated in tumour progression and regulated cell death; ho...