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Author

Azmatullah Khan

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Aug 2026

Identification, Design and Computational Insights of Hybrid Thiadiazole Linked Fused Thiazole-Isoxazole as Potent Dual Inhibitor of AChE/BChE Alzheimer's Disease

Alzheimer’s disease (AD), involves progressive cognitive impairment primarily associated with cholinergic dysfunction. Dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) continue to represent a validated and clinically relevant therapeutic approach for alleviating cholinergic deficits in...

Y. Khan, Hina Sarfraz, Azmatullah Khan et al. · 0 citations
Review Jul 2026

Isatin as a privileged scaffold for kinase inhibition: recent advances in anti-cancer research.

This review provides a comprehensive overview of recent advances in isatin-based kinase inhibitors, highlighting their design strategies, structure-activity relationships (SAR), and key molecular determinants of potency and selectivity.

A. Mushtaq, Azmatullah Khan, Akasha Maqbool et al. · 1 citation
Review Aug 2026

Multitargeted drug strategies for Alzheimer’s and Parkinson’s diseases

Recent advances in multitarget drug development for AD and PD targeting compounds targeting Aβ, BACE1, MAO-B, cholinesterases, metal-ion dyshomeostasis, oxidative stress, and inflammatory pathways are reviewed.

Azmatullah Khan, Abdullah Abdullah, Syeda Farwa Naqvi et al. · 0 citations

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