Azza E. Ismail

Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents

The rise of azole-resistant and the elevated prevalence of fungal infections in immuno-compromised cancer patients emphasize the necessity for strategies that can tackle both fungal resistance and tumor expansion. We postulated that the appropriate alteration of the azole pharmacophore through the inclusion of a 1,2,3-...