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B. A. Afful

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Open access Oct 2026

Mathematical modeling and optimal control of chagas disease transmission in evolving ecological environments

Chagas disease remains a major public health challenge in many endemic regions due to sustained transmission among humans, animal reservoirs, and Triatomine bug vectors. In this study, we develop and analyze an eleven-compartment deterministic model describing the transmission dynamics of Trypanosoma cruzi among human,...

B. A. Afful, Asante Christiana, M. O. Ohemeng · 0 citations
Preprint Jul 2026

Hybrid SINDy-EnKF in Learning Chikungunya Dynamics from Incomplete, Noisy or Partially Observed Data

A hybrid, data-driven model framework that combines Sparse Identification of Nonlinear Dynamics (SINDy) with the Ensemble Kalman Filter (EnKF) for sequential data assimilation improves prediction accuracy and provides a good reconstruction of unobserved trajectories under partial observability, a common constraint in r...

B. A. Afful, Changhong Mou, Luis F. Gordillo · 0 citations

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