Author

B. Aguilar

2 papers indexed here

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Open access Sep 2026

Patient-Derived Glioma Models Preserve Tumor Heterogeneity and Identify Stearoyl-CoA Desaturase1 (SCD1) as a Candidate Biomarker for Precision Immunotherapy

Background Pediatric and adult brain tumors, including glioblastoma, astrocytoma, ependymoma, and medulloblastoma, remain associated with poor prognosis despite advances in surgery, radiation, and chemotherapy. Therapeutic resistance, tumor heterogeneity, and treatment-related toxicity highlight the need for clinically...

Margarita Gutova, Eric Ma, H. Natri et al. · bioRxiv · 0 citations

Open access Aug 2026

Meditope-Enabled Chimeric Antigen Receptors Facilitate Plug-and-Play Control of T Cells

A versatile and modular platform that enables programmable control of CAR T-cell activity is reported, offering a new strategy to overcome tumor heterogeneity and immune suppression.

Cheng-Fu Kuo, Zhen Tong, Yi-Chiu Kuo et al. · Cancer immunology research · 0 citations