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Open access Sep 2026

HOTAIR lncRNA variants are associated with psoriasis susceptibility: A case-control study.

BACKGROUND Psoriasis is a chronic, immune-mediated skin disease characterized by keratinocyte hyperproliferation and persistent inflammation. Recent studies suggest that long non-coding RNAs (lncRNAs), such as HOX transcript antisense RNA (HOTAIR), may play critical roles in regulating inflammatory pathways involved in...

Egemen Akgun, F. M. Içduygu, B. Akşan et al. · 0 citations
Open access Jan 2026

A genetic variant of long non-coding RNA TINCR is associated with psoriasis in the Turkish population.

BACKGROUND TINCR and H19 are long non-coding RNAs known to be involved in keratinocyte proliferation and differentiation. The objective of this study was to investigate the contribution of TINCR rs2288947 and H19 rs217727 polymorphisms to the pathogenesis of psoriasis. METHODS The study group comprised 284 patients w...

Egemen Akgun, Fadime Mutlu İçduygu, B. Akşan et al. · 0 citations

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