Open access
Aug 2026
Age-stratified mutation patterns in early-onset colorectal cancer reveal distinct molecular features and therapeutic implications
Differences in mutations of key genes including a lower prevalence of APC mutations and increased SMAD4 mutations in younger individuals provides further supporting evidence that early-onset CRC may represent a distinct biological subtype of CRC.
L. Liu, A. Rose, A. Samaddar et al.
· ESMO gastrointestinal oncolo... · 0 citations