Open access
Jul 2026
Non-canonical signaling hubs upon inhibition of MyD88-ERK interaction in cancer
It is demonstrated that perturbation of the ERK-MyD88 complex rewires cellular signaling into cell-autonomous hubs that coordinate caspase activation with chemokine secretion, thereby driving a program of immunogenic cancer cell death.
Nader Hussein, Najwa Skafi, Thuy Ha Pham et al.
· Cell Death and Disease · 0 citations