Next-generation hybrid bioanalytical platforms and clinical integration of TDM technologies for precision monitoring to optimize last-resort antibiotic therapy
This review aims to critically evaluate emerging bioanalytical platforms, modeling frameworks, and decision-support systems for optimizing TDM of last-resort antibiotics, and proposes a three-tiered TDM model combining site-specific sensing, real-time analysis, and computational forecasting to improve antimicrobial ste...