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Author

B. Bhushan

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Oct 2026

Assessment of Unbound Rebastinib in Human Plasma and Serum Albumin by Equilibrium Dialysis Coupled with High-resolution Orbitrap Mass Spectrometry

Plasma protein binding (PPB) is a critical determinant of drug pharmacokinetics, as only the unbound fraction (fᵤ) of a drug is available for tissue distribution, target engagement, and clearance. However, the interaction of rebastinib with plasma proteins has not been fully elucidated to date. In this study, the free...

Suryakant Kumar, B. Bhushan, Bhumika Sharma et al. · 0 citations

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