Background/Objectives: Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with axicabtagene ciloleucel (axi-cel) improves outcomes in relapsed/refractory large B-cell lymphoma (LBCL), but many patients relapse despite retained CD19 expression. We explored baseline tumor transcriptional features associated with ev...
Jean Silva de Souza Resende, I. S. Giner, Maria Gabriela Custodio de Figueiredo et al.· Medical Science· 0 citations
Simple Summary CD19-directed chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of large B-cell lymphoma (LBCL), but many patients either do not respond or subsequently relapse. This structured narrative review examines clinical outcomes and biological factors associated with resistance and re...
Jean Silva de Souza Resende, I. S. Giner, Maria Gabriela Custodio de Figueiredo et al.· Cancers· 0 citations
CMA identified clinically relevant recurrent CNVs at neurodevelopmental loci even in a clinically nonsyndromic ASD cohort, highlighting the substantial influence of clinical and phenotypic selection on the diagnostic contribution of CMA.
Willian de Souza Santos, B. C. de Figueiredo, R. G. Mello et al.· Diagnostics· 0 citations
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