Review
Open access
Sep 2026
Consensus recommendations for the management of locally advanced rectal cancer
Background Locally advanced rectal cancer (LARC) considerably impairs quality of life (QoL) and compromises prognosis. Immunotherapy induces complete responses in most patients with mismatch repair deficient/microsatellite instability-high (dMMR/MSI-h) LARC, enabling organ preservation; however, challenges include acce...
R. Hofheinz, R. García-Carbonero, F. Ciardiello et al.
· ESMO gastrointestinal oncolo... · 0 citations