Background: Epilepsy is a frequent neurological disorder in childhood, with a significant impact on patients’ development and functionality. Some cases evolve into drug-resistant epilepsy (DRE), defined as persistent seizures regardless of proper treatment, and are associated with increased morbidity and a decreased li...
Isabel Braz, Aline Costa Carvalho, B. DeSouza et al.· ANPAbstract_CBN26· 0 citations
Background: Parkinson's Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons and the accumulation of α-synuclein. Beyond neuronal degeneration, neuroinflammation plays a central role in the pathophysiology of the disease. Microglia, the primary immune cells of the c...
Camilla Rodrigues Pereira da Silva, Alice Moura Dórea de Melo, Amanda Satomi Kimura Minami et al.· ANPAbstract_CBN26· 0 citations
The advancement of controlled clinical studies, combined with the use of molecular biomarkers, neuroimaging, and longitudinal cognitive assessment, may clarify the impact of these interventions on disease progression and contribute to the development of more targeted and safer therapies.
Camilla Rodrigues Pereira da Silva, Ana Beatriz Balão, Beatriz de Lima Soares et al.· ANPAbstract_CBN26· 0 citations
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