Open access
Jul 2026
Design and evaluation of engineered MyD88 fusion proteins for enhancing CAR-T therapy 2333869
It is demonstrated that functional outputs can be modulated via altering assembly thresholds as well as tuning signaling motifs, two parameters which help to define design goals for next-generation immunotherapies integrating innate and adaptive signals.
Alexander Partin, M. Daris, B. DiAndreth et al.
· Journal of Immunology · 0 citations