The mesolimbic dopamine system supports broad aspects of adaptive behavior including salience, learning, memory, and decision making, yet the structural organization supporting these functions remains incompletely mapped in humans. Using high-resolution 7T diffusion magnetic resonance imaging (up to N=173), we reconstr...
B. Elliott, Ranesh Mopuru, Linda J. Hoffman et al.· bioRxiv· 0 citations
Abstract The human brain is organized by large-scale functional gradients, but whether white-matter connectivity defines similarly reproducible and biologically interpretable axes of cortical, subcortical, and cerebellar organization remains unclear. Here, we introduce Structural Connectivity Gradient Mapping (SCGM), a...
Dardo Tomasi, B. Elliott, J. Sarlls et al.· Research Square· 0 citations
Importance Psychosis is strongly associated with striatal dopamine dysfunction, but noninvasive measures that capture variation in dopamine remain limited. Hemodynamic latency, which quantifies the timing of low-frequency blood oxygen level-dependent (BOLD) fluctuations, may provide a way to indirectly probe dopamine d...
Ranesh Mopuru, B. Elliott, Linda J. Hoffman et al.· bioRxiv· 0 citations
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