Author

B. Ford

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Open access Aug 2026

TIM3 blockade with hypomethylating therapy restores NK-cell and cytotoxic CD4+ T-cell activity in patients with AML or MDS.

The results suggest that anti-TIM3 combined with decitabine engages a distinct mechanism of immune activation compared to anti-PD1 and anti-CTLA4, preferentially expanding NK-cell and CD4+ T-cell populations.

Jani Huuhtanen, S. Forstén, B. Ford et al. · Cancer immunology research · 0 citations