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B. Gereben

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Open access Aug 2026

S14.1 - Tissue specific thyroid hormone signalling

The human thyroid gland primarily synthesizes thyroxine (T4), a metabolically stable prohormone requiring mostly extrathyroidal peripheral deiodination to T3 for cellular activity. The hypothalamic-pituitary-thyroid (HPT) axis maintains a relatively stable circulating thyroid hormone (TH) level. However, TH signaling...

B. Gereben · 0 citations

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