Sep 2026
FABP1‐Mediated Lipid Metabolic Reprogramming Buffers Lipotoxicity in Nephrolithiasis via Maintaining PPARγ Activity
Nephrolithiasis‐induced lipotoxicity is a critical driver of tubular cell death and renal function decline, yet targeted pharmacological interventions remain a major unmet clinical need. While Fatty Acid‐Binding Protein 1 (FABP1) is widely recognized as a passive injury biomarker, its active functional role in bufferin...
Qiu-Shi He, Zi-Yang Song, Zhi-Wei Jiang et al.
· The FASEB Journal · 0 citations