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Author

B. Hutten

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Review Open access Oct 2026

Towards a suitable biomarker for childhood screening for familial hypercholesterolemia: a systematic literature review

Abstract Familial hypercholesterolemia (FH) is a common genetic disorder causing elevated low-density lipoprotein cholesterol (LDL-c) concentrations from birth, resulting in a high risk of premature cardiovascular disease. Despite effective early treatment, FH remains underdiagnosed in children, highlighting the need f...

Vera H. de Kleijne, B. Hutten, A. Boelen et al. · 0 citations
Review Open access Sep 2026

Current, novel and emerging lipid-lowering therapies in pediatric familial hypercholesterolemia.

As therapeutic options expand and agents with greater LDL-C reductions become available, personalized treatment strategies will become increasingly important to achieve LDL-C targets and may ultimately shift from stepwise intensification approaches toward early intensive treatment.

Eelke Houter, S. E. van den Bosch, B. Hutten et al. · 0 citations

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