Salvinorin A in humans: A systematic review of pharmacokinetics, pharmacodynamics, and safety.
Salvinorin A, the principal psychoactive constituent of Salvia divinorum, is a highly selective κ-opioid receptor agonist and a rare example of a κ-opioid receptor-mediated psychedelic drug. Preclinical work of salvinorin A has shown promising effects in neuropsychiatric animal models. However, human studies remain het...