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Author

B. Karslı

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Case report Aug 2026

Pharmacogenetic hypersensitivity to somatropin in a child with severe growth hormone deficiency and MC4R p.V166I variant

Findings suggest that MC4R p.V166I may modulate peripheral GH/IGF-1 signaling and act as a pharmacogenetic modifier of GH responsiveness in patients carrying the MC4R p.V166I variant.

Ertuğrul Sancak, Muammer Büyükinan, Ahmet Fatih Yılmaz et al. · 0 citations

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