Open access
Aug 2026
Molecular mechanisms governing peptide nanodisc assembly and stability.
Using coarse-grained molecular dynamics (CG-MD), this work captures the de novo formation of 4F nanodiscs with DMPC and reveals a multistep assembly pathway involving nucleation, fusion, and ellipse-to-disc maturation, validating the ability of CG-MD to resolve nanodisc assembly mechanisms.
Bikash R. Sahoo, B. Krishnarjuna, Thirupathi Ravula et al.
· Journal of Colloid and Inter... · 0 citations