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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

B. Larijani

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Open access Sep 2026

Design and synthesis of carbazole–acrylamide–pyridinium hybrids as dual acetylcholinesterase/butyrylcholinesterase inhibitors and evaluation of their cytotoxic profile on SH-SY5Y and HEK293 cell lines

A novel series of seventeen carbazole–acrylamide–pyridinium-N-phenylacetamide hybrids (12a–q) was designed and synthesized as dual inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) for potential Alzheimer's disease therapy. Their inhibitory activity was evaluated against both enzymes using tacr...

A. Taherkhani, Halil Şenol, Y. Valizadeh et al. · 0 citations
Aug 2026

Design, synthesis, and in vitro/in vivo evaluation of novel diphenyl-1,2,4-triazine-3-yl-thioacetamide-chalcone hybrids as potent α-glucosidase inhibitors targeting type 2 diabetes.

Findings identify compound 9b as a promising lead α-glucosidase inhibitor with potent in vitro and in vivo antihyperglycemic activity, warranting further investigation for the treatment of type 2 diabetes.

Elika Salehi Ghalehsefid, Mohammad Halimi, Hassan Mohammadi et al. · 0 citations

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