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Author

B. Lenz

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6 papers indexed here

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Clinical trial Open access Oct 2026

Pharmacologically altered androgens, brain activation and response inhibition in a stop-signal task in male heavy drinkers

Heavy episodic drinking (HED) is highly prevalent in men and a major risk factor for Alcohol Use Disorder (AUD). Previous studies indicated an influence of testosterone (T) on AUD, and dihydrotestosterone (DHT) was linked to alcohol consumption, impulsivity, and response inhibition. As the role of androgens in AUD and...

Marlene Kundlacz, R. Boroumand-Jazi, S. Hoffmann et al. · 0 citations
Open access Oct 2026

Impaired Control Symptoms in Alcohol Use Disorder Show Convergent Associations Across Behavioral and Neural Markers of Inhibitory Control and Drinking Behavior

Background Deficits in inhibitory control are considered a central feature of alcohol use disorder (AUD), yet behavioral and neuroimaging findings have been inconsistent. One potential explanation is the marked heterogeneity of AUD, which encompasses multiple symptom dimensions that may differ in their underlying neuro...

J. Böhmer, Pablo Reinhardt, Marco Bottino et al. · 0 citations
Open access Aug 2026

Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health—informing a Delphi process

This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...

Bernd R. Förstner, S. Böttger, Timm Seegert et al. · 0 citations
Open access Oct 2026

Real-world alcohol cue exposure and drinking risk in alcohol use disorder

Alcohol-related cues are thought to contribute to drinking in alcohol use disorder (AUD), but their contribution in daily life remains difficult to separate from changing social contexts and internal states. We used ecological momentary assessment in two independent cohorts of non-treatment-seeking individuals, compris...

A. Ghadami, Abhijit Sreepada, I. Reinhard et al. · 0 citations
Open access Aug 2026

Fluctuations in real-life drinking in alcohol use disorder: A one-year longitudinal study using gamified tasks of decision making and cognitive control.

It is found that smartphone-based, gamified tasks show promise to identify periods of heightened risk paving the way for mechanism-based, real-time interventions in AUD: specific decision-making alterations precede changes in consumption.

Hilmar Zech, Maria Waltmann, D. Reichert et al. · 0 citations
Sep 2026

Sex-Moderated and Sex-Specific Effects of Adverse Childhood Experiences on Neural Alcohol Cue Reactivity and Daily Craving in Individuals With Alcohol Use Disorder.

OBJECTIVE Adverse childhood experiences (ACEs) play a pivotal role in alcohol use disorder (AUD), and evidence suggests that this role differs by sex. Neural alcohol cue reactivity may represent one pathway linking ACEs to alcohol craving and use. The authors examined whether cue reactivity is differentially associated...

L. Rötzer, J. Zaiser, S. Hoffmann et al. · 0 citations

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