Breast cancer is one of the most commonly diagnosed malignancies among women worldwide and is frequently curable when identified at an early stage. However, advanced and metastatic disease continue to account for a substantial proportion of breast cancer-related deaths, particularly among patients with aggressive subty...
Shayla Murray, Matthew Becker, B. Lim· Frontiers in Oncology· 0 citations
Introduction Trastuzumab deruxtecan (T-DXd) has transformed treatment for HER2-expressing malignancies, yet pneumonitis remains a potentially fatal toxicity. Most pneumonitis data derive from breast cancer cohorts, but risk factors and outcomes in non-breast solid organ tumors are poorly characterized. Materials and Me...
A. Attia, Jose Carlos Tuesta Delgado, Alexia Dayan Lecaros Zavalla et al.· Journal of Immunotherapy and...· 0 citations
Purpose: SMARCB1-deficient renal medullary carcinoma (RMC) is an ultra-rare, lethal malignancy refractory to therapies approved for other renal cell carcinomas, and its rarity makes randomized trials logistically unfeasible. We investigated whether wild-type epidermal growth factor receptor (EGFR) is a therapeutically...
N. Zacharias, Eric S Rupe, Xinyue Chen et al.· Clinical Cancer Research· 0 citations
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