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Review Open access Oct 2026

Inflammatory breast cancer among advanced breast malignancies: diagnostic, microenvironmental, and therapeutic challenges of the rare amongst the common

Breast cancer is one of the most commonly diagnosed malignancies among women worldwide and is frequently curable when identified at an early stage. However, advanced and metastatic disease continue to account for a substantial proportion of breast cancer-related deaths, particularly among patients with aggressive subty...

Shayla Murray, Matthew Becker, B. Lim · 0 citations
Open access Sep 2026

Trastuzumab Deruxtecan-Associated Pneumonitis in Non-Breast Solid Tumors: A Retrospective Cohort Study

Introduction Trastuzumab deruxtecan (T-DXd) has transformed treatment for HER2-expressing malignancies, yet pneumonitis remains a potentially fatal toxicity. Most pneumonitis data derive from breast cancer cohorts, but risk factors and outcomes in non-breast solid organ tumors are poorly characterized. Materials and Me...

A. Attia, Jose Carlos Tuesta Delgado, Alexia Dayan Lecaros Zavalla et al. · 0 citations
Open access Aug 2026

Panitumumab-Based EGFR Blockade in SMARCB1-Deficient Renal Medullary Carcinoma: Preclinical Basis and Prospective Clinical Activity

Purpose: SMARCB1-deficient renal medullary carcinoma (RMC) is an ultra-rare, lethal malignancy refractory to therapies approved for other renal cell carcinomas, and its rarity makes randomized trials logistically unfeasible. We investigated whether wild-type epidermal growth factor receptor (EGFR) is a therapeutically...

N. Zacharias, Eric S Rupe, Xinyue Chen et al. · 0 citations

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