Norovirus is a leading cause of acute gastroenteritis (AGE) worldwide, with significant morbidity and mortality, particularly in young children and older adults. This study characterizes the global prevalence and diversity of norovirus genotypes among sporadic cases. A review of English-language studies (published 2002...
J. Cannon, Christine Kim, Duncan Mahood et al.· Viruses· 0 citations
Background Effective vaccines against Shigella, the leading bacterial cause of diarrheal disease globally, could prevent morbidity and mortality from shigellosis as well as limit antibiotic resistance. Several Shigella vaccine candidates are in late stages of development, and the design of large Phase 3 trials in targe...
A. Amin, M. Garcia Quesada, Daniel Trudell et al.· PLoS Medicine· 0 citations
BACKGROUND
Noroviruses are a leading cause of acute gastroenteritis worldwide, yet no licensed vaccines currently exist. Antibody-mediated immunity provides protection, but the relationship between norovirus exposure dose and antibody kinetics remains unclear.
METHODS
We analyzed longitudinal data on histo-blood grou...
Murphy John, Yang Ge, W. Billings et al.· Journal of Infectious Diseas...· 0 citations
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