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Author

B. Martinac

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Open access Sep 2026

Opening threshold and kinetics of the MscL mechanosensitive channel are regulated by its periplasmic loop

Mechanosensitive channels of large conductance (MscL) protect bacteria from hypo-osmotic stress by opening a large pore in response to membrane tension. The transmembrane TM1 and TM2 helices together with the N-terminal amphipathic helix function as the primary force-sensing structural domains, whereas the role of the...

K. Duru, Paul Rohde, H. Hafezi et al. · 0 citations

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