Association of the Schizophrenia Risk Locus rs10866912 with Cerebral Volumes, Diet, and Psychosis in the UK Biobank
Background: Leading schizophrenia GWAS signals require evaluation of their pathological significance across diverse ancestries. rs10866912 reached genome-wide significance in our Indian ancestry GWAS of schizophrenia; its risk allele reduces expression of NAPRT, the rate-limiting enzyme in the brain’s principal NAD+-sy...