Open access
Sep 2026
Design of bifunctional pyridinophane ligands as Mn2+ MRI agents for diagnostic imaging of Alzheimer's disease
The diazapyridinophane scaffold is established as a viable first-generation platform for blood–brain barrier (BBB)–permeable Mn2+ MRI contrast agents and both the bifunctional chelators and their Mn2+ complexes exhibit appreciable affinity for Aβ aggregates.
T. El Sayed, Akhil Patel, Ke-Rui Xu et al.
· Inorganic Chemistry Frontier... · 0 citations