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Open access Sep 2026

Lysosomal polygenic risk score in Parkinson's disease across populations.

Background: Lysosomal dysfunction has been implicated in Parkinson's disease (PD) pathogenesis. However, lysosomal polygenic risk scores (lyso-PRS) have not been evaluated extensively in PD across populations. Objectives: (1) Evaluation of lyso-PRS (lyso-PRS) performance for PD risk across populations; (2) Comparison o...

W. Sun, K. Brockmann, I. Wurster et al. · 0 citations
Open access Sep 2026

Striatal representations and network correlates of digital motor scores in Parkinsons disease

Digital health technology (DHT) enables to detect and quantify charateristics motor dysfunction in Parkinsons disease (PD). However, the understanding of the relationship between dopaminergic nigrostriatal denervation and quantitative composite digital motor scores (DMS) captured by DHT remains largely limited to date....

B. Roeben, D. Blum, B. G. Montes et al. · 0 citations

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