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B. Tarantino

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ISAAC: Intervention-Based Structural Auditing of Deep Models for Transcription Factor Binding

ISAAC (Intervention-based Structural Auditing for Computational Models), a post-hoc framework that evaluates model behaviour through controlled, sequence-level interventions grounded in position weight matrices, supports structural auditing as a necessary complement to accuracy and attribution in XAI for genomics.

B. Tarantino, Paolo Giudici · 0 citations

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