Author

B. van de Water

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Open access Oct 2026

Functional Mammary Gland Organoids From Human Induced Pluripotent Stem Cells

The human mammary gland arises through sequential lineage restrictions from surface ectoderm to hormone-responsive bilayered epithelium, yet a tractable in vitro model that captures these events has remained elusive. Here, we established a stepwise differentiation protocol that directs human induced pluripotent stem ce...

Roshni Nair, Maarten Ganne, Larissa Mourão et al. · bioRxiv · 0 citations

Open access Sep 2026

Applicability of NAMs to support a read-across based hazard assessment workflow for systemic toxicity: a conazole case study.

This work explores the applicability of new approach methodologies (NAMs) using a read-across approach to predict systemic toxicity with liver as the critical target organ, and derive a point of departurefor the target compound (TC) difenoconazole. Eight conazoles were used as source compounds (SCs), alongside metaboli...

Barira Islam, Jenny Irwan, L. Wijaya et al. · Archives of Toxicology · 0 citations