Author

B. Van den Eynde

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Open access Oct 2026

Chemotherapy enhances cancer vaccine efficacy and expands stem-like TCF1+CD8+ T cells.

Therapeutic cancer vaccines are increasingly tested in clinical settings alongside standard-of-care treatments that often include chemotherapy, yet whether chemotherapy synergizes with cancer vaccines remains unclear. Here, we tested heterologous prime-boost viral vector vaccines in combination with various chemotherap...

Laurine Noblecourt, Amanda Wicki, Ashwin K. Jainarayanan et al. · Cancer Cell · 0 citations

Review Aug 2026

Adrenergic regulation of cancer immunity.

The nervous and immune systems engage in extensive bidirectional crosstalk that shapes tumor progression and therapeutic response. Among the neuro-immune pathways involved in cancer, adrenergic receptor signaling has emerged as a key regulator of the tumor microenvironment. In this review, we summarize current understa...

Jingjing Zhu, Pierre-Hubert Desimpel, C. Gérard et al. · Clinical Cancer Research · 0 citations

Open access Sep 2026

Thymic age and peripheral residence time determine antitumor competence of CD8+ T cells.

These findings establish developmental imprinting as an important determinant of CD8+ T cell heterogeneity and identify CXCR3+IL-18Rα+ CD8+ T cells as key effectors for antitumor immunity.

Yuan-Qin Yang, Yun-Yi Wang, Amanda Wicki et al. · Proceedings of the National... · 0 citations