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Open access Sep 2026

Exploratory study on blood and urine transcriptomes for identifying miRNA biomarkers in pediatric febrile bacterial and viral infections

Modern clinical practice lacks rapid, reliable, and non-invasive methods to distinguish between bacterial and viral infections. It negatively impacts the effectiveness of treatment and increases the risk of unnecessary antibiotic administration and thus antibiotic resistance spread. Using microRNA (miRNA) biomarkers in...

T. Kiseļova, B. Vilne, Gunda Zvīgule-Neidere et al. · 0 citations
Open access Aug 2026

Polygenic risk score for early identification of coronary artery disease in a real-world clinical setting within the Latvian patient population

Study objective Polygenic risk scores (PRS) are increasingly recognized for their potential to improve coronary artery disease (CAD) prediction beyond traditional clinical models. This study evaluated the utility of genome-wide association study (GWAS) - derived PRS and pathway-specific PRS (PS-PRS) in the Latvian popu...

E. Kanašniece, Elita Ozola, L. Bardina et al. · 0 citations

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