Author

B. Viswanath

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Sep 2026

A transdiagnostic evaluation of adult temperamental profiles and their interactions with childhood adversities across major psychiatric disorder.

BACKGROUND Temperamental profiles and adverse childhood experiences (ACEs) have been reported in most major psychiatric disorders. However, the nature of this relationship is complex and under-studied. METHODS A total of 1162 individuals (N = 532 affected; N = 457 unaffected first-degree relatives (FDRs) and N = 173...

P. Dayalamurthy, S. Balachander, S. P. Lakkireddy et al. · Journal of Affective Disorde... · 0 citations

Aug 2026

Clinical correlates of APOE ε4 homozygosity in Alzheimer's dementia: findings from an Indian cohort.

In this Indian cohort, APOE ε4 homozygosity reflects increased susceptibility and familial aggregation of AD but does not confer a more severe or distinct phenotype, suggesting ancestry- specific expression of APOE ε4 gene-dose effects.

Pratibha Vinod, C. Arampady, Somdatta Sen et al. · Neurodegenerative Disease Ma... · 0 citations

Open access Jul 2026

Genetics and epigenetics in tumor necrosis factor-alpha (TNF-α) and transmembrane 6 superfamily member 2 (TM6SF2) in alcohol induced liver cirrhosis

Background Alcohol dependence and cirrhosis are key outcomes of increased alcohol use, with genetic factors increasingly implicated. A functional promoter variant (rs361525) in the TNF-α gene may contribute to ALD pathogenesis, while a loss-of-function variant (rs58542926) in TM6SF2 modifies liver disease progression....

B. Shankarappa, J. Mahadevan, Pratima Murthy et al. · Frontiers in Medicine · 0 citations